The science
Two hormones.
One mechanism.
Tirzepatide is the first medication to act on both GIP and GLP-1 receptors. Here is what that means for a man in his forties.
20.9%
average body weight lost at 72 weeks on tirzepatide 15 mg¹
2
hormone receptors targeted: GIP and GLP-1
1
weekly injection, at home, in seconds
Appetite and food noise
Tirzepatide acts on the receptors that regulate hunger. You feel satisfied with less, and the constant background negotiation with food goes quiet.
Energy and blood sugar
By improving insulin sensitivity and slowing how quickly food leaves the stomach, blood sugar rises and falls more gently. Most men describe the afternoon collapse disappearing first.
Weight, hormones and drive
Fat tissue converts testosterone into estrogen. Sustained weight loss is associated with healthier testosterone levels, better sleep and improved sexual function. Your baseline panel measures where you stand.
Protecting what you have built
Rapid weight loss can cost lean mass. The protocol pairs medication with protein targets and resistance training so strength holds while fat comes off.
The benefits begin
before the scale moves.
Weight loss is the visible result. The metabolic shift underneath it starts earlier: energy, sleep, blood pressure, and the numbers your physician watches most closely.
Supports a healthier heart¹
Improves sleep for men with sleep apnea¹
Eases pressure on knees and joints²
Titrated deliberately.
Tolerated comfortably.
Starting low and stepping up is clinical best practice. This is the shape of the first six months.
Begin your assessmentExample monthly
dose increases
1Ease in2.5 mg
Building tolerance
Mild early effects such as nausea are expected and short-lived. They are a sign the medication is active.
2Ramp up5 mg
Increasing dose
Side effects become less common as your dose, and your results, increase in step.
3Step up7.5 mg
Incremental progress
Moving up deliberately keeps you comfortable on treatment until you reach your target dose.
4Maintenance10 to 15 mg
Sustaining results
Hold the dose that supports your goals, adjusted with your physician at each quarterly review.
Physician access, any hour
Message your physician at any time. Dose changes are reviewed by a licensed clinician.
Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Prime is not affiliated with or endorsed by Eli Lilly and Company.
1. Up to 21% body weight reduction: based on the 72-week SURMOUNT-1 trial of tirzepatide 15 mg in adults with obesity or overweight (mean change 20.9%). Individual results vary.
2. Tirzepatide is FDA-approved for chronic weight management as Zepbound® and for type 2 diabetes as Mounjaro®. Compounded tirzepatide is not FDA-approved.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required. Not available in all 50 states. The Prime program includes nutrition guidance, technological tools, and medications prescribed based on what your physician determines is medically appropriate and necessary for you.
FSA/HSA eligibility and coverage varies by plan provider.
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Build this.
Begin your private assessmentFour minutes. Private. Reviewed by a physician.