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The Prime compounded tirzepatide vialRX ONLY • LICENSED US PHARMACY • Rx
FSA & HSA eligible

Tirzepatide Protocol

  • Dual-action GLP-1 and GIP medication, prescribed weekly
  • Up to 21% body weight reduction in clinical trials¹
  • Baseline labs and quarterly physician reviews included

Safety information

The Tirzepatide Protocol
  • A once-weekly injectable GLP-1 and GIP medication for weight management
  • Reduces hunger and slows how quickly food leaves the stomach
  • Prescribed around your baseline labs, with quarterly physician reviews
About the ingredients
  • Same active ingredient as Mounjaro® and Zepbound®
  • Mimics two gut hormones, GIP and GLP-1, released after eating to signal fullness
  • Helps regulate appetite and blood sugar
  • Slows digestion so you stay full for longer
  • Compounded in a licensed US pharmacy to your physician’s prescription

Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Prime is not affiliated with or endorsed by Eli Lilly and Company.

How to take
  • Inject once a week, on the same day each week
  • Use the abdomen, thigh or upper arm, rotating sites
  • With or without food, at any time of day
  • Store vials refrigerated and follow the included instructions
Side-effect care, built in
  • Generic ondansetron included at no extra cost if prescribed, to prevent nausea as you adjust
  • A low starting dose, stepped up deliberately
  • Message your care team at any hour with questions or side-effect tips

Precision, in a vial.

Start your assessment

Rx only, pharmacy made

Compounded by a licensed US pharmacy to your physician’s prescription.

Two hormones, one mechanism

Acts on both GLP-1 and GIP receptors, not one.

Clinically measured

Up to 21% body weight reduction over 72 weeks in trials.¹

Vial or pen

The compounded vial or the brand-name pen, across a range of doses.

1. In a 72-week clinical trial of tirzepatide 15 mg in adults with obesity or overweight. Individual results vary.

A man reading his protocol on a tablet in his study at night

How it works

  1. 1

    Assessment

    Four minutes, online. Your history, your goals and your numbers so far.

  2. 2

    Labs

    A baseline metabolic and hormone panel, drawn near you or at home. Ordered the same day.

    Included with membership.

  3. 3

    Physician review

    A licensed physician reads your results and builds the protocol, or tells you plainly why it is not right for you.

  4. 4

    Protocol delivered

    Medication ships discreetly within days. Quarterly reviews and repeat labs from there.

Begin your assessment
A Prime physician

Everything handled,
in one membership.

Alongside medication, if prescribed, you receive:

  • Baseline metabolic and hormone panel
  • A physician-built dosing protocol
  • Quarterly physician reviews with repeat labs
  • Private messaging with your care team, any hour
  • Nutrition and training guidance for men over 40
  • Side-effect support, with anti-nausea medication if prescribed
Start your assessment
Active Prime Membership required. Mounjaro® is FDA-approved for the treatment of type 2 diabetes and is available only to patients who meet clinical eligibility criteria, as determined by a licensed physician, who may prescribe it off-label for weight management based on independent clinical judgment. Mounjaro® is a registered trademark of Eli Lilly and Company. Prime is not affiliated with or endorsed by Eli Lilly and Company.
Macro of a tirzepatide vial on dark marble

A more complete molecule

Tirzepatide activates both GIP and GLP-1 receptors, the two gut hormones that tell your brain you are full. One weekly dose, two signals, and greater weight reduction than single-action GLP-1 therapy in head-to-head trials.

Compounded vial,
or brand-name pen?

Two forms of the same molecule, for different preferences. Your physician reviews your assessment and recommends the one that fits.

Results from individual clinical trials. Products have not been directly compared.

Tirzepatide Protocol

Tirzepatide Protocol

Starts at
$299/mo
billed monthly, membership required†
Lose up to
21%¹
How to take
Weekly injection
Active ingredient
Tirzepatide
Mounjaro® Pen

Mounjaro® Pen

Starts at
$449/mo
billed monthly, membership required†
Lose up to
21%¹
How to take
Weekly injection
Active ingredient
Tirzepatide
†Medication is billed separately and only if prescribed. An active Prime Membership ($149/month) is required and includes your baseline panel, physician reviews and care team access. Membership does not guarantee a prescription. Mounjaro® is FDA-approved for the treatment of type 2 diabetes and is available only to patients who meet clinical eligibility criteria, as determined by a licensed physician, who may prescribe it off-label for weight management based on independent clinical judgment. Mounjaro® is a registered trademark of Eli Lilly and Company. Prime is not affiliated with or endorsed by Eli Lilly and Company. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required. Not available in all 50 states.

Titrated deliberately.
Tolerated comfortably.

Starting low and stepping up is clinical best practice. This is the shape of the first six months.

Begin your assessment

Example monthly
dose increases

1Ease in2.5 mg

Building tolerance

Mild early effects such as nausea are expected and short-lived. They are a sign the medication is active.

2Ramp up5 mg

Increasing dose

Side effects become less common as your dose, and your results, increase in step.

3Step up7.5 mg

Incremental progress

Moving up deliberately keeps you comfortable on treatment until you reach your target dose.

4Maintenance10 to 15 mg

Sustaining results

Hold the dose that supports your goals, adjusted with your physician at each quarterly review.

Physician access, any hour

Message your physician at any time. Dose changes are reviewed by a licensed clinician.

Questions, answered plainly.

Begin your assessment
What does the Prime Membership include?

A baseline metabolic and hormone panel, a physician-built dosing protocol, quarterly physician reviews with repeat labs, private messaging with your care team at any hour, nutrition and training guidance written for men over 40, and side-effect support from your care team. Medication is billed separately, and only if prescribed.

How much does it cost?

The membership is $149 per month and can be cancelled at any time from your account. If prescribed, tirzepatide starts at $299 per month for the compounded vial and $449 per month for the brand-name Mounjaro® pen. There are no consultation fees and nothing is billed until your physician has reviewed your assessment.

Will I need to come in?

No. Your assessment, physician review and every follow-up are handled online. Your baseline labs are drawn at a partner laboratory near you, or at home where our mobile phlebotomy service is available. Most men spend less than fifteen minutes a month on their protocol.

How private is this?

Completely. Your records are encrypted, your medication ships in unmarked packaging, and nothing is shared with employers, insurers or anyone else without your written consent. We do not bill insurance, so no claim is ever filed.

Why do you insist on labs?

Because weight is usually the symptom, not the cause. Your baseline panel shows what is driving it: metabolic markers, thyroid function, testosterone and more. Your physician builds the protocol around those numbers, then rechecks them each quarter so the plan keeps pace with your body.

Do I need insurance?

No. Prime does not bill insurance, which means no plan restrictions, no prior authorizations and no claims on your record. Pricing is transparent and paid directly.

Can I use an FSA or HSA?

We recommend paying with a standard card and submitting your receipt for reimbursement. Eligibility and coverage vary by plan provider.

Who qualifies for tirzepatide?

A state-licensed physician reviews your health history, weight, goals and lab values. Tirzepatide is generally considered for adults with a BMI of 30 or higher, or 27 or higher with a weight-related condition. The decision is always the physician’s.

Is Prime available in my state?

We currently serve patients in 38 states, and availability depends on state regulations and pharmacy partners. If we cannot treat you yet, we will tell you during the assessment and notify you when that changes.

I have already tried a GLP-1. Can I switch?

Yes. Tell us what you are taking and at what dose during your assessment. Your physician will review your history and, where appropriate, build a transition plan so you keep the progress you have made.

How long will I stay on treatment?

Tirzepatide is designed for long-term use. Many men move to a maintenance dose once they reach their goal. Your physician will plan that with you at your quarterly reviews, including whether and how to taper.

What happens after the weight comes off?

Your quarterly reviews continue. Your physician tracks your labs, protects the muscle you have built and adjusts your protocol as your numbers change. The relationship does not end when the scale stops moving.

When will I notice a difference?

Most men notice a quieter appetite within the first two weeks. Meaningful weight loss typically shows over the first two to three months as your dose increases, with results continuing through the first year.

Can my dose change during treatment?

Yes. Request a dose review from your care team at any time. If your physician decides an adjustment is right, they write a new prescription and explain the change. Pricing may vary by dose.

Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Prime is not affiliated with or endorsed by Eli Lilly and Company.

1. Up to 21% body weight reduction: based on the 72-week SURMOUNT-1 trial of tirzepatide 15 mg in adults with obesity or overweight (mean change 20.9%). Individual results vary.

2. Tirzepatide is FDA-approved for chronic weight management as Zepbound® and for type 2 diabetes as Mounjaro®. Compounded tirzepatide is not FDA-approved.

Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required. Not available in all 50 states. The Prime program includes nutrition guidance, technological tools, and medications prescribed based on what your physician determines is medically appropriate and necessary for you.

FSA/HSA eligibility and coverage varies by plan provider.